Faster Than Glucosamine!

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INTRODUCTION TO RESEARCH ON FASTER THAN GLUCOSAMINE

With Faster Than Glucosamine! our name is in essence our claim. It is a bold statement, but fully backed with clinical research. We feel that Faster Than Glucosamine! is at least Three Times Faster and Three Times More Effective than glucosamine and or chondroitin.When it comes to health we believe that consumers have a right to the truth.

The term “Clinically Proven” is used very loosely with some health products. Fundamentally one would expect the term to mean that a specific product has been tested and shown to work.

The truth is that with several supplements an ingredient is added, which then enables a company to make the “Clinically Proven” statement without the actual combination product EVER BEING TESTED.

Often a different form of the ingredient is used than was actually studied. With glucosamine for example there are several forms of the supplement.

Or a reduced amount of an ingredient is added. If clinical trials on a medicine were conducted using 1 gram, would it then be fair to say that the product has been clinically proven if only a ¼ gram is in a formula?

The bottom line is that you have to ask if the health product has been clinically researched. And you should ask the results, as “Clinically Proven” can mean many things. For example, clinically proven can mean that a product was shown to be safe and have no reference to efficacy, or clinically proven can in fact mean that a product has been proven not to work. We feel that if there is published research, then why not make it available?

As a case in point, in 2007 national TV ads were running in which a company claimed to have a clinically proven formula with the same ingredients (glucosamine hydrochloride and chondroitin sulfate) as used in the trial conducted by the National Institute for Health or NIH. The irony is that the stated results of this study (see below) were: “Overall glucosamine and chondroitin sulfate were not significantly better than placebo in reducing knee pain…” Most people would assume that a clinical trial conducted by the NIH would be highly credible, which we believe it was. And most importantly that the medicine tested was found to be highly effective, otherwise why would a company even refer to it? In this instance, this just simply was not the case. Again you need ask just what the results were.

Faster Than Glucosamine has been studied with seventeen (17) animal and clinical studies, with six (6) studies presented at scientific meetings and four (4) published in pre-eminent scientific journals – two of which have been published in the prestigious medical journal, The Journal of Rheumatology.

At Hope Science we are committed to doing our best to help educate consumers and physicians alike. Below you will find the research conducted specifically on Cetylated Fatty Acids (CFA) or Faster Than Glucosamine! The results of these studies are the foundation for our enthusiasm and validate our use of the term “Clinically Proven”. Below you will find our interpretation of the research and the study itself. We provide our interpretation in easy to read language, as medical manuscripts tend to be very technical, lengthy and are often difficult to understand for non-scientists.

(Click on study title to view full study as published)

MEDICUS RESEARCH / JK UDANI
CFA for the Improvement of Functional Ability and Pain in Patients with Knee Osteoarthritis

This is recently completed research on oral cetylated fatty acids (CFA) for osteoarthritis (OA) of the knee. This was a double blind, placebo controlled trial with 93 patients.

Patients receiving CFA improved pain wise in comparison to those receiving the placebo pills. However a perhaps more interesting aspect of this study was that it measured an objective functional parameter in addition to pain, which of course is considered subjective in nature. Patients were tested prior to starting medication and then after 2, 4 and 8 weeks to see how far they could walk in 6 minutes. Presumably the pain of OA of the knee would cause one to walk slower and if pain relief occurred, one could then speed up and walk farther in the given time. Patients receiving CFA were able to walk 233 feet farther after just 2 weeks. And they continued to improve. After 8 weeks they walked on average 537 feet farther than they could at the beginning of the clinical trial. Just as impressive was the difference between the two groups, as those receiving the placebo did not improve and in fact were able to walk a slightly shorter distance after 8 weeks.

This clinical trial was presented at the Scripps Medical Conference for Integrated Medicine in San Diego in 2007. The paper won first prize in the “Original Research Category” out of the 90 papers presented.

NEW ENGLAND JOURNAL of MEDICINE – 2006
Glucosamine and Chondroitrin Sulfate in Combination for OA

This GAIT (Glucosamine/Chondroitin Arthritis Intervention Trial) is the largest multi center clinical trial completed to date for evaluating the efficacy and safety of glucosamine and chondroitin to treat osteoarthritis (OA). Conducted by the National Institute for Health (NIH), the trial was conducted at 16 medical sites across the country.

The conclusions of the study were: Glucosamine and chondroitin alone or in combination did not reduce pain effectively in the overall group of patients with osteoarthritis of the knee. Exploratory analysis suggests that the combination of glucosamine and chondroitin sulfate may be effective in the subgroup of patients with moderate-to-severe knee pain.

Our interpretations of the results are that glucosamine and/or chondroitin if they do in fact help, offer on average only mild relief. To be considered effective in this trial only a 20% reduction in pain was needed. The fact that only 20% improvement was needed and did not occur often enough in the majority of those receiving glucosamine and/or chondroitin to be statistically different than placebo is a telling statistic. We feel based on this and the other studies presented here that Faster Than Glucosamine! is indeed much more effective than glucosamine and/or chondroitin.

The onset of pain relief was also very slow or gradual in those treated with glucosamine and/or chondroitin. After 4 weeks there was very little difference between the treatment and placebo groups. Even after the full 24 weeks of the study the difference between treatment and placebo groups was minimal. Compared to the results of the other studies presented here it seems clear that Faster Than Glucosamine! is indeed just that-FASTER. To view information about "Questions and Answers: NIH Glucosamine/Chondroitin Arthritis Intervention Trial GAIT NCCAM Backgrounder" go to:

http://nccam.nih.gov/research/results/gait/qa.htm

JOURNAL of STENGHTH and CONDITIONING – 2005
Effects of CFA Topical Cream with Knee Osteoarthritis

In this study 40 patients with osteoarthritis (OA) of the knee were studied to see if applying CFA cream twice daily for a month would lead to an improvement in standing postural stability or the ability to simply stand in one place. Presumably knee pain due to OA would limit the ability to stand for extended periods. After one month testing revealed that the CFA group did improve significantly, whereas those receiving the placebo did not. This clinical trial reinforced the positive results obtained in an earlier OA trial using the topical CFA cream.

JOURNAL of STENGHTH and CONDITIONING – 2005
CFA Topical Cream Reduces Pain and Improves Function in Arthritis Patients

Faster Than Glucosamine! cream is comprised of CFA and a minimal amount of menthol (1.25%). This clinical trial was designed to test whether menthol affected the efficacy, since previous tests were conducted without menthol. Patients with either OA of the knee, elbow or wrist were tested. One week of treatment of the cream containing menthol was found to be similarly effective for reducing pain and improving functional performance as prior tests without menthol.

JOURNAL of RHEUMATOLOGY –2004
Effect of CFA Topical Cream on Functional Mobility

This double blind, placebo controlled clinical trial investigated whether CFA topical cream could improve the functional mobility of patients with OA of the knees, since these patients typically have impaired physical performance, presumably at least in part due to pain. Patients were tested at baseline and then 30 minutes later to determine the short-term affects and also 30 days later after applying the cream twice daily for long-term benefits.

The CFA cream was found to increase the range of motion of the knees, improve the ability of patients to ascend and descend stairs, made it easier to get up from a sitting position and improved the balance of patients stepping down.

Most interesting was the result that after only 30 minutes of the first application of CFA cream there were real improvements. Further improvements were recorded after a months use indicating that the cream provides not only short-term benefit, but also cumulative long-term benefit as well with regular daily use.

JOURNAL of RHEUMATOLOGY – 2002
CFA Improves Knee Function in OA Patients

This placebo controlled clinical trial of CFA in oral form was the first to investigate whether CFA or Faster Than Glucosamine! could be used to treat osteoarthritis (OA) of the knee. The overall function of the knees, as well the range of motion improved in the patients receiving CFA. The success of this study paved the way for the other studies above.